New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides.

نویسندگان

  • S P McCormick
  • S L Taylor
  • R D Plattner
  • M N Beremand
چکیده

Mutant strains of Fusarium sporotrichioides NRRL 3299 deficient in the ability to synthesize T-2 toxin were examined on solid rice medium. Five novel alicyclic trichothecenes were isolated: 11 alpha-hydroxytrichodiene; tricho-9-ene-2 alpha,3 alpha,11 alpha-triol; tricho-9-ene-2 alpha,3 alpha,8 alpha,11 alpha-tetraol; tricho-9-ene-2 alpha,3 alpha,8 beta,11 alpha-tetraol; and tricho-9-ene-2 alpha,3 alpha,11 alpha,16-tetraol.

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Accumulation of Trichothecenes in Liquid Cultures of a Fusarium sporotrichioides Mutant Lacking a Functional Trichothecene C-15 Hydroxylase.

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Disruption of TRI101, the gene encoding trichothecene 3-O-acetyltransferase, from Fusarium sporotrichioides.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 55 9  شماره 

صفحات  -

تاریخ انتشار 1989